Ipamorelin

Main effect: stimulates GH release; human hormone-response studies exist.

Selectivity: early experiments found relatively selective GH stimulation.

Distinct pathway: acts through a different receptor from GHRH analogs.

Gut research: studied for motility after surgery; the trial found no significant

efficacy benefit.

Pairing rationale: GHRH-pathway stimulation may amplify GH release.

Safety: chronic-use data are limited; serious IV-trial events do not alone

establish causation.